Hyperkalemia is a condition where the potassium level is abnormally high in the bloodstream. Potassium is an important electrolyte that is involved in the electrical activity of the heart, muscles, and nerves. You should consider hyperkalemia in dialysis/renal patients, acutely dehydrated patients, and patients with evidence of severe muscular discomfort or prolonged physical activity (i.e. after running a marathon, or in a prolonged crush scenario).
Potassium plays a role in maintaining the resting membrane potential of cardiac cells. Under normal conditions, potassium is more concentrated inside the cells compared to the outside. When there is an increased potassium level in the outside, there is less of a potential between the inside and outside of the cell. This can result in cardiac abnormalities such as bradycardia, ventricular fibrillation, or asystole. There can also be a delay in conduction velocity resulting in a heart block or even cardiac arrest.
Symptoms of hyperkalemia may include palpitations, irregular heartbeat, chest pain, and fainting. Drugs given in the pre-hospital setting can stabilize the cardiac membranes and prevent arrhythmia or death. It is essential to address the underlying cause of hyperkalemia and provide rapid treatment.
Advanced Life Support for Suspected Hyperkalemia
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Establish IV/IO access and immediate 12-lead EKG
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Continuous cardiac monitoring
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Administration of calcium if there are EKG changes or as patient is being extricated from a prolonged crush injury (calcium will stabilize the cardiac membranes and help prevent arrhythmias)
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Calcium administration does not directly lower potassium levels, but rather reduces the risk of cardiac arrhythmias
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Calcium Chloride 1 gram IV bolus, may repeat in 10 minutes if no response
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If the patient is hypotensive: administer 0.9% NaCl en route in 500 cc boluses until systolic BP is greater than 90
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Sodium Bicarbonate will shift potassium out of the blood stream and back into the cells and can be given if persistent EKG changes after calcium administration
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Albuterol can also help shift potassium into the cells and can be given if persistent EKG changes after calcium administration
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Frequent re-assessment of patient’s appearance, vital signs, EKG changes, symptoms
The goal of these interventions is to stabilize the patient’s condition, manage life-threatening arrhythmias, and lower potassium levels until definitive care (ex. dialysis) can be provided in a hospital setting.
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